Effectiveness of Auricular Acupressure in the Treatment of Chemotherapy Induced Nausea and Vomiting in Ovarian Cancer and Endometrial Cancer
Study ID: TCTR20141110001
Current status: Recruiting
Last Updated: November 10, 2014
Tracking Information
Date of Registration in Primary Registry: November 09, 2014
Date of First Enrollment: September 11, 2014 (Anticipated)
Target Sample Size: 40
Last Updated Date: November 10, 2014
Primary Outcome(s):
  • Outcome name: comparison of nausea & vomiting outcome between experimental group and control group
       Metric/method of measurement: Rhodes index score
       Time point: 7 days
       Safety Issue?: No


  • Key Secondary Outcomes:
  • Outcome name: the incidence of chemotherapy induced nausea and vomitig
       Metric/method of measurement: Rhodes index score
       Time point: 7 days
       Safety Issue?: No


  • Descriptive Information
    Public Title: Effectiveness of Auricular Acupressure in the Treatment of Chemotherapy Induced Nausea and Vomiting in Ovarian Cancer and Endometrial Cancer
    Scientific Title: Effectiveness of Auricular Acupressure in the Treatment of Chemotherapy Induced Nausea and Vomiting in Ovarian Cancer and Endometrial Cancer : A Double-blinded Randomized Controlled Trial
    Brief Summary:
    Detailed Description:
    Study Design: Allocation: Randomized controlled trial
    Control: Placebo
    Study Endpoint Classification: Efficacy Study
    Intervention Model: Parallel
    Number of Arms: 2
    Masking: Single Blind (Masked Roles: Subject)
    Primary Purpose: Supportive Care
    Study Phase: Phase 2
    Health Condition(s) or Problem(s) Studied: patient who diagnosed ovarian cancer or endometrial cancer , chemotherapy first cycle of Paclitaxel and carboplatin
    Study Arms:
  • Arm: 1
  • Intervention Name: standard treatment with auricular acupressure
    Type: Experimental
    Classification: Device
    Descriptions: standard treatment with auricular acupressure with magnetic ear seed 4 point each side, advise patient to pressure the point 10 minutes before meal
  • Arm: 2
  • Intervention Name: standard treatment with placebo
    Type: Placebo Comparator
    Classification: Device
    Descriptions: standard treatment with auricular acupressure with foam ear seed 4 point each side (no pressure effect), advise patient to pressure the point 10 minutes before meal
    Recruitment Information
    Recruitment Status: Recruiting
    Estimated Enrollment: 40
    Study Start Date (First enrollment): September 11, 2014
    Primary Completion Date: January 31, 2015
    Inclusion Criteria:
    Inclusion Criteria
    Gender: Female
    Age Limit: Minimum 20 Years : Maximum 80 Years
    patient who diagnosed ovarian cancer or endometrial cancer
    treatment with first cycle of paclitaxel and carboplatin
    can reading and writing on Thai
    Exclusion Criteria
    pregnant women
    can not reading and writing on Thai
    allergy to manetic
    Accept Healthy Volunteers: No
    Countries of Recruitment Thailand
    Contact for Public Queries:
    Contact for Public Query's Name: Kanokwan Yontawin
    Phone: 0804400276
    Email: bkyontawin@gmail.com
    Postal Address: Rajavithi Hospital
    State/Province: Bangkok        Postal Code: 10400
    Country: Thailand
    Administrative Information
    Primary Registry Site: Thai Clinical Trials Registry
    Trial Identification Number: TCTR20141110001
    Secondary Identifying Numbers: Nil known
    Source(s) of Monetary or Material Supports: Rajavithi Hospital
    Study Primary Sponsor: Rajavithi Hospital
    Study Secondary Sponsor: 1.) Rajavithi Hospital
    Contact for Scientific Queries:
    Contact for Scientific Query's Name: Kanokwan Yontawin
    Phone: 0804400276
    Email: bkyontawin@gmail.com
    Postal Address: Rajavithi Hospital
    State/Province: Bangkok        Postal Code: 10400
    Country: Thailand
    Contact for Scientific Query's Name: Kanokwan Yontawin
    Phone: 0804400276
    Email: bkyontawin@gmail.com
    Postal Address: Rajavithi hospital
    State/Province: Bangkok        Postal Code: 10400
    Country: Thailand
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